MaQxan - Now it is clinically proven
MaQxan® is the branded Marigold Extracts – Lutein, Zeaxanthin, Lutein Ester, and Xanthophyll all made from own cultivated Tagetes Erecta flower by your trusted manufacturer
THE BEST LUTEIN & ZEAXANTHIN
MaQxan® is the branded Marigold Extracts – Lutein, Zeaxanthin, Lutein Ester, and Xanthophyll all made from own cultivated Tagetes Erecta flower by your trusted manufacturer; Ingex Botanicals.
Over the past 17 years, we offer “Seed to Shelf” traceability for all our 250 grades of Marigold Extract standardizations. Our well-established Quality Management System (QMS) ensures 100% transparency in all stages of operations starting from Marigold cultivation to Lutein, Zeaxanthin, Lutein Ester, and Xanthophyll packaging.
MaQxan® grades are carefully manufactured Marigold Extract range of carotenoids through validated manufacturing processes that preserve the macular pigments viz Lutein, Zeaxanthin, and Meso – Zeaxanthin in its natural composition to deliver the best benefits for Age-Related Macular Degeneration (AMD) protection, Blue Light Protection, improvement in MPOD (Macular Pigment Optical Density), improvement in Visual Performance parameters including contrast sensitivity, photo-stress recovery, disability glare, etc.
These Lutein, Zeaxanthin, Lutein Ester, and Xanthophyll grades are responsibly developed over decades to use as trusted ingredients in the formulation ranging from Pediatric to Geriatric health supplements. MaQxan® is the best Lutein and Zeaxanthin ingredient customized for ready-to-use in carotenoids formula and vision support supplements.
Ingex Botanicals is the leading manufacturer of Carotenoids – Lutein, R, R-Zeaxanthin, and Meso-Zeaxanthin made from Marigold flowers and customized for different applications like Food fortification, functional beverages, Gummies, Healthy desserts, Natural food color, Dairy products fortification, nutraceutical formulations, functional feed ingredients, and various pharmaceutical dosage forms.
MaQxan - Lutein, Zeaxanthin and Lutein Ester beyond Eye health
1. Skin Health (Cosmetic Benefits)
MaQxan range of Marigold Extracts – Lutein, Zeaxanthin, Meso-Zeaxanthin are also effective in “beauty within” concept cosmetic application. Many scientific studies reported that Lutein protected the skin against the damage induced by solar radiation. Studies also reported the beneficial effects of lutein intake on skin elasticity and hydration. We have optimized these carotenoid pigments to be compatible for use in beauty shots and functional beverages.
2. Cognitive functions (Brain Health)
Many scientific studies and some clinical studies have proved that Lutein is effective in improving memory and other measures of cognitive functions. Better eye health compliments stress management and also helps in improving sleep quality.
3. Cardiovascular health
Cardiovascular health partly depends on the activation of inflammatory cytokines, therefore, nutrients and drugs that favorably influence the cytokine cascade might effectively prevent Cardiovascular damage. Many studies in humans have also provided evidence for a beneficial role of Lutein supplementation, lowering the blood concentrations of inflammatory cytokines, while favoring the secretion of anti-inflammatory cytokines.
4. Effects on Metabolic disorders
Lutein is also proposed in certain metabolic disorders. Specifically, its effects have been studied on lipid profile management. It is also known to improve insulin sensitivity.
5. Lung function
Lutein is known to have a beneficial effect on lung function. Higher intake of Lutein was associated with significant improvement in forced vital capacity and forced expiratory volume.
6. Bone Health
Regular Lutein intake is known to help increase bone mineral density and prevent bone loss in elderly subjects.
Clinical Study -1 (MaQxan 202)
A Randomised Placebo-Controlled Clinical Trial To Evaluate The Efficacy Of Marigold Extract On Cognitive Performance And Mood In Adults With Stroke And Parkinson’s Disease
This clinical study was to assess the impact of MaQxan 202, a proprietary formulation, on cognitive function in individuals aged 35 to 75 years who suffer from cognitive dysfunction. The study was randomized, double-blind, and placebo controlled. Each capsule of MaQxan 202 contained Extract of Marigold flowers, which is equivalent to 10mg of Lutein and 1mg of Zeaxanthin. The participants received two capsules of MaQxan 202 per day, providing a daily dose of 20mg of Lutein and 2mg of Zeaxanthin. Methods: The study recruited 30 individuals who had been diagnosed with cognitive dysfunction resulting from either Parkinson's disease or stroke. The participants were block-randomized and divided into two groups, G1 and G2. Group G1 received MaQxan 202, while Group G2 received a placebo for a duration of five weeks. Compliance was assessed by conducting participant interviews and questionnaires. The participants underwent cognitive performance testing using the Standardized Cognitive Assessment Revised (SCAr) at the beginning of the study and at weeks 1, 2, 3, 4, and 5. Results: The SCAr test results showed that 46.6% of the individuals in the treatment group exhibited notable improvement in cognitive abilities. In contrast, none of the participants in the placebo group showed any improvement in cognitive function throughout the study period. Conclusion: The results indicate that taking the Lutein supplement formulation MaQxan 202 for five weeks can enhance cognitive function in people who suffer from cognitive dysfunction due to Parkinson's disease or stroke. These findings suggest that MaQxan 202 supplementation could be a hopeful intervention for individuals seeking to preserve and enhance their cognitive abilities. Findings of this study gives hope for further research on Cognitive benefits of MaQxan 202.
The Efficacy Of Marigold Extract On Cognitive Performance And Mood In Adults
Surprising Benefits of MaQxan: Beyond Eye Health
Macular Pigments, namely Lutein and Zeaxanthin, have been traditionally associated with promoting healthy eyesight. However, cutting-edge research has unveiled their potential benefits that extend beyond eye health, particularly in the realm of cognitive function and brain well-being.
The brain is susceptible to oxidative stress and inflammation, which can lead to cognitive decline over time. Thankfully, carefully processed and scientifically formulated Lutein and Zeaxanthin have shown remarkable abilities to counteract oxidative stress and reduce inflammation, thereby promoting overall brain health.
Studies have demonstrated that higher levels of Lutein in the bloodstream are linked to better cognitive performance and a decreased risk of cognitive decline in older adults. By neutralizing harmful free radicals, Lutein acts as a protective shield for brain cells, preserving their health and functionality.
Interestingly, insufficient Lutein intake has been associated with an increased risk of age-related macular degeneration (AMD), a condition that shares risk factors with cognitive decline. Unfortunately, the average Lutein intake in adults remains low, leaving the elderly particularly vulnerable due to factors like poor nutrition, reduced senses, changed food habits, and economic constraints.
The positive impact of Lutein extends beyond adulthood; observational studies suggest its crucial role in brain development and cognition during early life. Infants primarily obtain Lutein from breast milk, making the mother's intake essential for their cognitive development.
Lutein's presence in brain regions associated with memory and learning indicates a direct influence on brain tissues and functions.
Furthermore, higher Lutein intake or blood levels have been linked to a reduced risk of cognitive decline in older adults, suggesting that consistent consumption of Lutein-rich foods or scientifically validated supplements may protect against age-related cognitive impairment. By promoting the health and integrity of neurons responsible for transmitting information, Lutein plays a pivotal role in maintaining cognitive function.
MaQxan® is a branded Lutein-Zeaxanthin that has shown promising evidence of improving cognitive health. A clinical study conducted on 30 subjects using standardized Cognitive assessment revised (SCAR) for 5 weeks revealed notable improvements in cognitive function in 46.6% of the treatment group with MaQxan®.
Ingex Botanicals, the leading Lutein and Zeaxanthin manufacturer in India, developed a proprietary form of the combination from selected marigold flowers cultivated and harvested under strict and validated protocols, showcasing good efficacy during Cognitive health studies.
Moreover, MaQxan® strictly adheres to safe and green manufacturing methods, using only ethanol, enabling its use in various forms, from kids' formulas to geriatric products targeting cognitive health. Stringent quality checks for residual solvents, pesticides, heavy metals, and microbial contaminations ensure the safety of vulnerable populations.
While this section has focused on Lutein's effects on cognition, there are exciting discoveries yet to come.
Stay tuned to this page for updates on additional surprising effects of MaQxan.
Clinical Study -2 (MaQxan 204)
A randomized, double blind placebo-controlled cross-over clinical study to evaluate the effects of Lutein and Zeaxanthin MaQxan® (204) on Macular Pigment Optical Density (MPOD) and eye stress response through protecting photoreceptor cells from blue light effects; 3 arm, 2 sequence.
Macular pigment (MP), consisting of lutein (L) and zeaxanthin (Z), is believed to provide retinal protection against photo-oxidative damage. The current study investigates the response to supplemental MaQxan® (204) lutein and zeaxanthin in terms of macular pigment optical density (MPOD). The aim of this study was to determine the distribution of MaQxan® (204) in the healthy macula and how these variables relate to various demographic factors. 60 subjects were enrolled in the trial as per the inclusion criteria. Three groups of subjects were created: A, B, and C. All the subjects were given MaQxan® (204) and placebo as per the randomization chart prepared computationally. As the study is double-blinded, subjects getting MaQxan® (204) or placebo were coded. This three-arm study had A, B, and C groups, where the A group got MaQxan® (204) for the complete 8 months, the B group got MaQxan® (204) for the first 4 months and Placebo for the next 4 months, and the C group got placebo for the first 4 months and MaQxan® (204) for the next 4 months. Macular pigment optical density (OD) at 30 eccentricity at the baseline time point ranged from 0.08 to 1.04, and it was highly connected with better visual performance. After supplementing MaQxan® (204) after 8 months, the average MPOD (at 30 eccentricity) increased from 0.41 to 0.57. MaQxan® (204), supplementation improved most individuals' visual performance and considerably enhanced MPOD after 4 months of consumption. MaQxan® (204) may be a useful therapeutic agent in managing the protection of photoreceptor cells against diseases and blue light effects.
Healthy Eyes
The role of Lutein & Zeaxanthin
Everyone wishes to enjoy an excellent vision throughout their lifetime. Routine eye checkups and a diet rich in carotenoids are important for healthy eyes. Carotenoids are pigments that give vibrant red, orange, yellow and green colors to fruits and vegetables.
The macula is the pigmented area in the retina of the human eye. Since Macula has the highest concentration of photoreceptors in the retina; it produces the sharpest vision. Free Lutein, Zeaxanthin, and Meso Zeaxanthin concentrations are more in Macula and hence they are known as Macular Pigments.
Lutein and Zeaxanthin are generally fat-soluble carotenoids that function as anti-oxidants protecting cells from free radicals. About four decades of research establishes that Free Lutein, Zeaxanthin and Meso Zeaxanthin in macula filters shorter wavelength light ie blue light and prevents age-related macular degeneration (AMD).
Lutein, Zeaxanthin, and Meso-Zeaxanthin are the three dietary carotenoids present in “macular pigment”. These three carotenoid pigments are responsible for our ability to perceive colors. The macular pigments selectively filter out image-degrading visible blue light for sharper vision. Lutein is also known as “the eye vitamin”.
Rising eye disorders, such as age-related macular degeneration (AMD), and increasing eye health awareness among the general population, are expected to fuel the growth of the eye health supplements market.
Age-related macular degeneration (AMD) is the leading cause of irreversible severe visual loss in people of higher age and hence the geriatric population is at greater risk of eye disorders.
Almost all visible blue light passes through the cornea and lens and reaches the retina. This light may affect vision and could prematurely age the eyes.
Digital eyestrain: Blue light emitted from mobile phone screens and other digital devices can decrease contrast leading to digital eyestrain. Fatigue, dry eyes, bad lighting, or how you sit in front of the digital screen can cause eyestrain. Symptoms of eyestrain include sore or irritated eyes and difficulty focusing.
Retina damage: Some studies suggest that continued exposure to blue light over time could lead to retinal cell damage. This can cause vision problems like age-related macular degeneration.
Though the blue light exposure received from screens is small; the concern over the long-term effects of screen exposure is due to the proximity of the screens and the time spent looking at them.
Impact of COVID-19 on Eye health supplement.
With the new norm of daily life after the pandemic, people of all age groups are glued to the screens of digital gadgets resulting in increased screen exposure and invariably the blue light. Kids and the office-going population have been the most affected age groups where the blue light effect is more. This may lead to the rise in the number of people with eyesight disorders due to increased screen time.
Lifestyle & Diet: Observational studies have suggested an inverse relationship between dietary or serum lutein and risk for age-related macular degeneration and cataracts. The best way to guard against blue light damage is to reduce our level of exposure. Limit the time you spend on computers or with electronic devices, and take regular breaks from staring at LED screens. But with the inset of current lifestyle, avoiding all the screens is not feasible. It’s important to remember that our eyes have a natural level of Lutein and a healthy diet or supplement intake can help us keep these levels topped up. While hundreds of “superfoods” have been labeled over the years, nothing has shown as much promise as the carotenoid vitamin, Lutein for eyesight. Together with its sidekick, Zeaxanthin, this antioxidant works to protect both your eyes and skin.
Reasons to select MaQxan as your Trusted Lutein and Zeaxanthin Brand
1 %
01
Traceability - Seed to Shelf.
03
Testing of each batch before release
05
Free from Harmful solvents
07
ETO (Ethylene Tri Oxide) free
02
PAH (Polycyclic Aromatic Hydrocarbons) free
04
Free from Synthetic Colours
06
Free from Synthetic Preservatives
08
assurance of year-round availability
09
Price stability in both season and offseason.
11
Free from Ethoxyquin.
13
Free from Allergens
15
Non-GMO verified
10
Our product is 100% Natural
12
MaQxan is Vegan
14
Highly Stable Lutein
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Promised 24x7 customer support
Grades Offered
Free Lutein
General Grades
Free Lutein Powder - 5 to 80%
Free Lutein Oil - 5 to 40%
Free Lutein Granules - 5 to 30%
Water Soluble Grades
Free Lutein W S Powder - 5 to 20%
Free Lutein W D Powder - 5 to 20%
Free Lutein W S Granules - 5 to 20%
Free Lutein W D Granules - 5 to 20%
Free Lutein + Zeaxanthin
Powder - 5:1, 10:1, 10:2, 20:2, 20:4
Oil - 5:1, 10:1, 10:2, 20:2, 20:4
Lutein Esters
General Grades
Lutein Ester Powder - 5 to 80%
Lutein Ester Oil - 5 to 30%
Lutein Ester Granules - 5 to 30%
De-odorized Lutein Ester
Lutein Ester D O Powder 5 - 20%
Lutein Ester D O Granules 5 - 20%
Lutein Ester + Ester Zeaxanthin
Powder - 10:1, 20:1
Oil - 10:1, 20:1
Zeaxanthin
General Grades
Zeaxanthin Powder - 5 to 65%
Zeaxanthin Oil - 5 to 30%
Zeaxanthin Granules - 5 to 30%
Water Soluble Grades
Zeaxanthin W S Powder - 5 to 20%
Zeaxanthin W D Powder - 5 to 20%
Zeaxanthin W S Granules - 5 to 20%
Zeaxanthin W D Granules - 5 to 20%
Free Lutein + Zeaxanthin
Powder - 5:1, 10:1, 10:2, 20:2, 20:4
Oil - 5:1, 10:1, 10:2, 20:2, 20:4
Meso Zeaxanthin
General Grades
Meso Zeaxanthin Powder - 5 to 65%
Meso Zeaxanthin Oil - 5 to 30%
Meso Zeaxanthin Granules - 5 to 30%
Water Soluble Grades
Meso-Zeaxanthin WS Powder - 5 to 20%
Meso Zeaxanthin WD Powder - 5 to 20%
Meso Zeaxanthin WS Granules - 5 to 20%
Meso Zeaxanthin WD Granules - 5 to 20%
Free Lutein + Meso Zeaxanthin
Powder - 5:1, 10:1, 10:2, 20:2, 20:4
Oil - 5:1, 10:1, 10:2, 20:2, 20:4
Free from harmful bacteria and other pathogenic microorganisms. Safe to use in all formulations as per various regulations.
Longer shelf life compared to other brands for all variants.
Accelerated & Real-time stability data available on all grades
Clean Label
KOSHER & HALAL Certified
Manufactured in a cGMP- complying manufacturing facility.
Environment-friendly green technologies being used in cultivation and processing.
We encourage farmers to use Bio-fertilizers and Bio-pesticides in Marigold cultivation
Customized standardizations are possible based on customer requirements
Regulatory and Quality Assurance support available 24x7
250 grades of Marigold Extract standardizations
And many more....